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Semax
Semax is a synthetic heptapeptide analog of the adrenocorticotropic hormone fragment ACTH(4-10), supplied as a high-purity lyophilized powder. Its amino acid sequence is Met-Glu-His-Phe-Pro-Gly-Pro, often abbreviated MEHFPGP. In research settings, Semax is used to study neurotrophin expression, CNS signaling, neuroprotection models, and peptide effects on BDNF, NGF, monoaminergic signaling, and stress-response pathways. Semax includes a C-terminal Pro-Gly-Pro sequence that distinguishes it from the native ACTH(4-10) fragment and is associated with improved peptide stability.
Save up to 15% when you buy more!
| Quantity | Discount | Price |
|---|---|---|
| 1 | 0% | $49.00 |
| 2 - 5 | 5% | $46.55 |
| 6 - 10 | 10% | $44.10 |
| 11 - 15 | 15% | $41.65 |
Product details
Amino Acid Sequence
H-Met-Glu-His-Phe-Pro-Gly-Pro-OH
Molecular Formula:
C₂₂₁H₃₆₆N₇₂O₆₇S
Molecular Weight:
~813.9 g/mol
PubChem CID:
9811102
CAS Number:
80714-61-0
Vial Size:
3 mL
Contents:
Lyophilized powder, white/off-white color
Mechanism of action
ACTH(4-10) Analog Profile
Semax is derived from the ACTH(4-10) peptide region but replaces the C-terminal portion of native ACTH(4-10) with Pro-Gly-Pro. This gives Semax the sequence Met-Glu-His-Phe-Pro-Gly-Pro. In research models, Semax is studied as a neuroactive ACTH-fragment analog rather than as a corticosteroid or direct adrenal hormone.
Neurotrophin Expression
Semax is widely studied for its effects on neurotrophin-related signaling. Preclinical research has examined changes in brain-derived neurotrophic factor, nerve growth factor, and related receptor systems after Semax exposure. This makes Semax useful in models focused on neuronal survival, synaptic plasticity, adaptive CNS signaling, and neurotrophic pathway regulation.
BDNF / TrkB Pathway Research
Research has reported Semax-associated changes in BDNF expression and TrkB-related signaling in brain-region-specific models. BDNF is a key neurotrophic factor involved in neuronal survival, plasticity, and stress adaptation. Because of this, Semax is often used in studies examining how ACTH-fragment analogs influence BDNF-linked CNS pathways.
Storage & handling
Storage:
Store the lyophilized vial in a cool, dry area protected from direct sunlight.
Certificate of Analysis
99%+ Purity
Guaranteed
30-day return policy
Rigorous
Testing
Always 3rd party tested
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Shipping
Sent same day
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24/7 Chat & Email
FAQs
Why Honest Peptide?
- Rigorous Testing, No Exceptions: Every batch is 3rd-party tested for purity, weight, and toxins—so you can shop with total confidence.
- Priced Right: As a family business, we keep costs low and pass the savings directly to you.
- Here for You: Fast shipping and real human support, every single time.
Do you test your products and provide COAs?
Yes! Every product goes through multiple 3rd-party tests to verify purity, accurate weight, and that it’s toxin-free. Each test result is documented in a Certificate of Analysis (COA), which you can download directly from each product page or from our centralized COA library.
What if I have more questions?
We’re here to guide and support. Please reach out to hello@honestpeptide.com and we’ll respond within 1 business day.
What is your shipping policy?
Your order will be processed in 1–2 business days from the East Cost and shipped with UPS or FedEx Ground (2-5 business days). At this time, we only ship to the United States.
How should I store my peptides?
In lyophilized (powder) form, store in freezer for up to 2 years. In reconstituted form, store in fridge and use in 4-8 weeks.
What is your refund policy?
We are serious about customer satisfaction. If you are not happy with your order, please reach out within 30 days and we will replace or refund your order**.**
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