MOTS-C

$50.00

MOTS-C (Mitochondrial ORF of the Twelve S rRNA type-C) is a 16-amino-acid peptide encoded within the mitochondrial 12S rRNA gene. Identified in 2015, it functions as a mitochondrial-derived peptide (MDP) involved in regulating metabolic homeostasis. In preclinical and early human studies, MOTS-C enhances insulin sensitivity, promotes lipid and glucose metabolism, and increases exercise capacity. It is supplied as a high-purity lyophilized powder for use in laboratory research. 

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Product details

Amino Acid Sequence

Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg

Molecular Formula

C₁₀₁H₁₅₂N₂₈O₂₂S₂

Molecular Weight

2174.6 g/mol

PubChem CID

146675088

CAS Number

1627580-64-6

Vial Size

3ml

Contents

Lyophilized powder, white/off-white color

Mechanism of action

AMPK Activation

MOTS-C increases levels of AICAR and stimulates AMPK, leading to enhanced glucose uptake and fatty-acid oxidation.

Insulin Sensitivity

Improves glucose tolerance and insulin action in diet-induced obese mice; correlates with insulin signaling enhancement in skeletal muscle.

Exercise Mimetic Role

Circulating MOTS-C rises in humans during acute exercise; in mice, administration increases exercise performance and stress adaptation.

Cytoprotection

Acts as a “mitokine,” transmitting mitochondrial stress signals and promoting cellular resilience.

Storage & handling

Storage:

Store the lyophilized vial in a cool, dry area protected from direct sunlight.

MOTS-C

Certificate of Analysis

99%+ Purity
Guaranteed

30-day return policy

Rigorous

Testing

Always 3rd party tested

Fast & Free

Shipping

Sent same day
Free over $150

Customer

Service

24/7 Chat & Email

FAQs

Why Honest Peptide?
  1. Rigorous Testing, No Exceptions: Every batch is 3rd-party tested for purity, weight, and toxins—so you can shop with total confidence.
  2. Priced Right: As a family business, we keep costs low and pass the savings directly to you.
  3. Here for You: Fast shipping and real human support, every single time.
Do you test your products and provide COAs?

Yes! Every product goes through multiple 3rd-party tests to verify purity, accurate weight, and that it’s toxin-free. Each test result is documented in a Certificate of Analysis (COA), which you can download directly from each product page or from our centralized COA library.

What if I have more questions?

We’re here to guide and support. Please reach out to hello@honestpeptide.com and we’ll respond within 1 business day.

What is your shipping policy?

Your order will be processed  in 1–2 business days from the East Cost and shipped with UPS or FedEx Ground (2-5 business days). At this time, we only ship to the United States.

How should I store my peptides?

In lyophilized (powder) form, store in freezer for up to 2 years. In reconstituted form, store in fridge and use in 4-8 weeks.

What is your refund policy?

We are serious about customer satisfaction. If you are not happy with your order, please reach out within 30 days and we will replace or refund your order**.**

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