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CJC-1295 (No DAC)
CJC-1295 (No DAC) is a synthetic analog of growth-hormone–releasing hormone (GHRH), commonly referred to as modified GRF 1-29. It contains 29 amino acids and is designed to selectively activate the GHRH receptor (GHRHR) on pituitary somatotrophs, supporting research into pulsatile growth hormone secretion, hypothalamic-pituitary GH axis dynamics, and downstream IGF-1 signaling. Unlike CJC-1295 with DAC, the “No DAC” form does not include the drug-affinity-complex modification, giving it a shorter duration of action and making it useful in studies focused on transient GHRH receptor activation.
Save up to 15% when you buy more!
| Quantity | Discount | Price |
|---|---|---|
| 1 | 0% | $35.00 |
| 2 - 5 | 5% | $33.25 |
| 6 - 10 | 10% | $31.50 |
| 11 - 15 | 15% | $29.75 |
Product details
Amino Acid Sequence
H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH₂
Molecular Formula:
C₁₅₂H₂₅₂N₄₄O₄₂
Molecular Weight:
~3,367.9 g/mol
PubChem CID:
91976842
CAS Number:
863288-34-0
Vial Size:
3 mL
Contents:
Lyophilized powder, white/off-white color
Mechanism of action
GHRH Receptor Agonism & GH Secretion
CJC-1295 (No DAC) selectively activates the GHRH receptor on pituitary somatotrophs, stimulating adenylate cyclase and the cAMP/PKA signaling cascade. This pathway supports pulsatile growth hormone release in GH-axis research models.
Downstream IGF-1 Signaling
Growth hormone signaling stimulates hepatic and peripheral IGF-1 production, allowing researchers to study downstream anabolic, lipolytic, and tissue-remodeling pathways associated with the GH/IGF-1 axis.
Short-Acting GHRH Analog Profile
Because CJC-1295 (No DAC) lacks the DAC albumin-binding extension, it is shorter acting than DAC-modified CJC-1295. This makes it useful for research models where brief, pulse-like GHRHR activation is preferred over prolonged receptor exposure.
Storage & handling
Storage:
Store the lyophilized vial in a cool, dry area protected from direct sunlight.
Certificate of Analysis
99%+ Purity
Guaranteed
30-day return policy
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FAQs
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Yes! Every product goes through multiple 3rd-party tests to verify purity, accurate weight, and that it’s toxin-free. Each test result is documented in a Certificate of Analysis (COA), which you can download directly from each product page or from our centralized COA library.
What if I have more questions?
We’re here to guide and support. Please reach out to hello@honestpeptide.com and we’ll respond within 1 business day.
What is your shipping policy?
Your order will be processed in 1–2 business days from the East Cost and shipped with UPS or FedEx Ground (2-5 business days). At this time, we only ship to the United States.
How should I store my peptides?
In lyophilized (powder) form, store in freezer for up to 2 years. In reconstituted form, store in fridge and use in 4-8 weeks.
What is your refund policy?
We are serious about customer satisfaction. If you are not happy with your order, please reach out within 30 days and we will replace or refund your order**.**
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