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Not for human or animal consumption
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CAS 863288-34-0
Identity (M-S) passedHeavy metals clearedPurity (HPLC) Passed
Volume pricing Save up to 15% with quantity-based pricing. Discounts are applied automatically in cart.| Quantity | Discount | Per item price |
|---|---|---|
| 1Current Tier | 0% | $35.00 |
| 2 - 5Current Tier | 5% | $33.25 |
| 6 - 10Current Tier | 10% | $31.50 |
| 11 - 15Current Tier | 15% | $29.75 |
CJC-1295 (No DAC)
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Testing
Review current lot-specific analytical results and supporting documentation for each available strength.
Verified test results for the current batch
Identity (M-S) passed Heavy metals cleared Purity (HPLC) PassedProcess
A documented, step-by-step process designed to ensure consistency, transparency, and traceability
Representative samples are selected from each production lot
Samples are submitted to a qualified third-party laboratory for analytical testing
Analytical results are reviewed against our internal release specifications
Results and supporting documentation are published online before shipment
Research
Explore key technical details, molecular characteristics, and research context for this compound.
CJC-1295 developed from a longer history of growth hormone–releasing hormone research. Human GHRH was isolated and sequenced in 1982 from pancreatic tumors associated with acromegaly.¹ ² Investigators then showed that shorter fragments, including GHRH(1-29), retained growth hormone–releasing activity.³ ⁴ During the 1990s and 2000s, researchers developed modified GHRH analogs with greater resistance to enzymatic degradation. CJC-1295 added a drug-affinity-complex, or DAC, group designed to bind albumin and substantially extend exposure.⁵ ⁶ In 2006, studies in healthy adults reported prolonged increases in growth hormone and IGF-1, while growth hormone secretion remained pulsatile during continuous stimulation.⁵ ⁶ Naming later became confusing. In scientific literature, CJC-1295 generally refers to the long-acting DAC-containing molecule. In commercial research settings, “CJC-1295 No DAC” commonly refers to Modified GRF(1-29), a related but shorter-acting analog. CJC-1295 is therefore best understood as part of the historical effort to make GHRH signaling more durable – not as growth hormone itself.
CJC-1295 activates GHRH receptors on somatotroph cells in the anterior pituitary. This is the same receptor system used by endogenous hypothalamic GHRH.¹ ² The GHRH receptor couples to adenylyl cyclase, increasing cyclic AMP and activating protein kinase A. This signaling supports growth hormone synthesis and release from pituitary cells.³ ⁴ Growth hormone then acts on peripheral tissues, including the liver, to increase downstream IGF-1 signaling. Because CJC-1295 acts upstream, it stimulates endogenous growth hormone rather than supplying the hormone directly. Research on the DAC-containing form found that growth hormone secretion remained pulsatile even during prolonged receptor stimulation.⁶ DAC changes pharmacokinetics more than receptor identity. The DAC group binds albumin, extending exposure and producing sustained growth hormone and IGF-1 elevation in human studies.⁵ The shorter material commonly called CJC-1295 No DAC, or Modified GRF(1-29), activates the same receptor pathway but produces briefer signaling. The core mechanism is therefore GHRH receptor → cAMP/PKA → growth hormone → IGF-1, with DAC status determining duration.
Information
Answers to common questions about research use, testing, storage, ordering, and documentation.
CJC-1295 is supplied as a dry, lyophilized (freeze-dried) powder and should be white in color. If the material appears inconsistent with its documented specifications, contact our team for verification.
Every batch undergoes independent third-party analytical testing. Testing includes mass spectrometry for identity, HPLC for purity, net peptide content, heavy metals, fentanyl screening, and endotoxin testing. Full results are published in the applicable batch-specific COA or laboratory report.
Every batch must meet our release specifications before being made available for sale: confirmed molecular identity, ≥99% HPLC purity, peptide content no more than 10% below the stated amount, and successful completion of all applicable contaminant testing.
Locate the batch number printed on your product box, then scan the QR code on the vial to access our COA Library and find the matching report. Batch-specific COAs are also available directly on the product page. Each report contains independent third-party testing results, and previous batch reports are retained for historical reference
No. CJC-1295 is sold individually and does not include solvents or other accessories.
CJC-1295 should be kept tightly sealed and protected from moisture, light, and repeated temperature fluctuations. For shorter-term storage, refrigeration at 2–8°C may be appropriate, while freezer storage at approximately −20°C may be appropriate for longer-term preservation.
Orders placed on weekdays before our daily shipping cutoff typically ship the same business day. Orders placed after the cutoff, on weekends, or on holidays typically ship the next business day. Tracking is emailed once your order ships.
If there is a problem with your order, contact us within 30 days of delivery. Depending on the circumstances, we’ll arrange an appropriate replacement or refund.
Sale of this product is restricted to qualified researchers, laboratories, and research institutions. This material is supplied solely for controlled research use and is not intended for human consumption, veterinary use, therapeutic use, or clinical application. Purchase constitutes confirmation that the buyer is appropriately qualified and will use the material only for research purposes.
Our Quality Standards
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