Legal Disclaimer
All products on this site are for research and development, laboratory, or analytical use only; they are not for human consumption, medical, diagnostic, cosmetic, veterinary, or any other non-research application. The statements and products have not been evaluated by the U.S. Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease. Honest Peptide is not a compounding pharmacy or chemical compounding facility as defined under section 503A of the Federal Food, Drug, and Cosmetic Act, nor an outsourcing facility as defined under section 503B.
Tesamorelin
Tesamorelin is a synthetic 44-amino-acid analog of growth-hormone–releasing hormone (GHRH), supplied as a high-purity lyophilized powder. It is designed to activate the GHRH receptor on pituitary somatotrophs and is used in in vitro and preclinical research to study endogenous growth hormone release, GH-axis signaling, downstream IGF-1 activity, and metabolic pathway dynamics. Tesamorelin includes an N-terminal trans-3-hexenoyl modification that distinguishes it from native GHRH and improves peptide stability while preserving GHRH receptor activity. Unlike direct growth hormone, tesamorelin acts upstream by stimulating receptor-mediated GH release rather than supplying GH externally.
Save up to 15% when you buy more!
| Quantity | Discount | Price |
|---|---|---|
| 1 | 0% | $70.00 |
| 2 - 5 | 5% | $66.50 |
| 6 - 10 | 10% | $63.00 |
| 11 - 15 | 15% | $59.50 |
Product details
Amino Acid Sequence
trans-3-hexenoyl-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH₂
Molecular Formula:
C₂₂₁H₃₆₆N₇₂O₆₇S
Molecular Weight:
~5,135.9 g/mol
PubChem CID:
16137828
CAS Number:
218949-48-5
Vial Size:
3 mL
Contents:
Lyophilized powder, white/off-white color
Mechanism of action
GHRH / GRF Receptor Agonism
Tesamorelin acts as an analog of human growth-hormone–releasing hormone. It binds and stimulates GHRH / GRF receptors on pituitary somatotroph cells, activating the endogenous growth hormone release pathway. This receptor-level activity makes tesamorelin useful for studying pituitary GH secretion, GH pulse dynamics, and upstream control of the somatotropic axis.
Endogenous Growth Hormone Release
By stimulating the GHRH receptor, tesamorelin supports synthesis and pulsatile release of endogenous growth hormone from pituitary somatotroph cells.This distinguishes tesamorelin from recombinant growth hormone, which bypasses upstream hypothalamic-pituitary signaling and acts directly as the hormone itself.
Downstream IGF-1 Signaling
Growth hormone released from the pituitary can stimulate hepatic and peripheral production of insulin-like growth factor 1. IGF-1 is a major downstream mediator of GH-axis activity and is involved in anabolic signaling, tissue remodeling, and metabolic regulation.Tesamorelin is therefore useful in research models examining the relationship between GHRH receptor activation, GH release, IGF-1 response, and downstream endocrine signaling.
Storage & handling
Storage:
Store the lyophilized vial in a cool, dry area protected from direct sunlight.
Certificate of Analysis
99%+ Purity
Guaranteed
30-day return policy
Rigorous
Testing
Always 3rd party tested
Fast & Free
Shipping
Sent same day
Free over $150
Customer
Service
24/7 Chat & Email
FAQs
Why Honest Peptide?
- Rigorous Testing, No Exceptions: Every batch is 3rd-party tested for purity, weight, and toxins—so you can shop with total confidence.
- Priced Right: As a family business, we keep costs low and pass the savings directly to you.
- Here for You: Fast shipping and real human support, every single time.
Do you test your products and provide COAs?
Yes! Every product goes through multiple 3rd-party tests to verify purity, accurate weight, and that it’s toxin-free. Each test result is documented in a Certificate of Analysis (COA), which you can download directly from each product page or from our centralized COA library.
What if I have more questions?
We’re here to guide and support. Please reach out to hello@honestpeptide.com and we’ll respond within 1 business day.
What is your shipping policy?
Your order will be processed in 1–2 business days from the East Cost and shipped with UPS or FedEx Ground (2-5 business days). At this time, we only ship to the United States.
How should I store my peptides?
In lyophilized (powder) form, store in freezer for up to 2 years. In reconstituted form, store in fridge and use in 4-8 weeks.
What is your refund policy?
We are serious about customer satisfaction. If you are not happy with your order, please reach out within 30 days and we will replace or refund your order**.**
Subscribe
Unlock 10% off
